ART-CHEM-BB B021944

ART-CHEM-BB B021944 - Names and Identifiers

Name	2-(4-Methylpiperazin-1-yl)aniline
Synonyms	AKOS BB-7895 AKOS B021944 ASISCHEM Z51464 ART-CHEM-BB B021944 CHEMBRDG-BB 4010388 TIMTEC-BB SBB007133 2-(4-METHYLPIPERAZIN-1-YL)ANILINE 2-(4-Methylpiperazin-1-yl)aniline 2-(4-Methyl-1-piperazinyl)aniline 1-methyl-4-(2-aminobenzyl)piperazine 1-methyl-4-(2-nitrophenyl)piperazine 2-(4-METHYL-PIPERAZIN-1-YL)-PHENYLAMINE 4-(2-aminophenyl)-1-methylpiperazin-1-ium
CAS	180605-36-1
InChI	InChI=1/C11H17N3/c1-13-6-8-14(9-7-13)11-5-3-2-4-10(11)12/h2-5H,6-9,12H2,1H3/p+1

ART-CHEM-BB B021944 - Physico-chemical Properties

Molecular Formula	C11H17N3
Molar Mass	191.27
Density	1.092±0.06 g/cm3(Predicted)
Melting Point	101 °C
Boling Point	321.2±37.0 °C(Predicted)
Flash Point	146°C
Vapor Presure	0.000302mmHg at 25°C
Appearance	Solid
pKa	7.91±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
MDL	MFCD04035359

ART-CHEM-BB B021944 - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R34 - Causes burns R36 - Irritating to the eyes
Safety Description	S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3263 8/PG III
Hazard Note	Toxic
Hazard Class	IRRITANT
Packing Group	III

ART-CHEM-BB B021944 - Introduction

2-(4-Methylpiperazin-1-yl)aniline, chemical formula C11H14N2, is an organic compound. The following is a description of the nature, use, formulation and safety information:

1. Nature:
-Appearance: 2-(4-Methylpiperazin-1-yl)aniline is white crystal or crystalline powder.
-Solubility: Soluble in ethanol, chloroform and ether, slightly soluble in water.
-Melting point: About 134-135 ° C.
-Density: about 1.08g/cm³.
-Stability: relatively stable at room temperature.

2. Use:
-Drug intermediate: 2-(4-Methylpiperazin-1-yl)aniline can be used to synthesize some drugs, such as antihypertensive drug captopril.
-Dyes and pigments: This compound can also be used in the synthesis of dyes and pigments.

3. Preparation method:
- 2-(4-Methylpiperazin-1-yl)aniline has many preparation methods, one of which is commonly used by the reaction of p-nitroaniline with 1-(4-methylpiperazine) ethanone. The specific steps are: firstly performing an amide reaction between p-nitroaniline and 1-(4-methylpiperazine) ethanone, and then obtaining the target product through a reduction reaction.

4. Safety Information:
- 2-(4-Methylpiperazin-1-yl)aniline is a chemical and should follow the corresponding safety procedures when used.
-For specific safety information, such as hazard and toxicity, please refer to the relevant Safety Data Sheet (MSDS) or obtain relevant information from a reliable source.

Please note that the above content is for reference only. Please follow the relevant laboratory safety regulations and professional guidance for specific operations.

Last Update：2024-04-09 20:02:46